Successful Management of Meningitis and Sepsis Due to Multidrug-Resistant Elizabethkingia meningoseptica in an Infant

We report a case of a two-month-old male infant, born prematurely, who initially presented with fever, irritability, and elevated inflammatory markers. He was then diagnosed with <i>Elizabethkingia meningoseptica </i>meningitis and sepsis. Treatment included intravenous levofloxacin, ampicillin, and cefotaxime. Despite the bacterium's multidrug resistance and high reported morbidity and mortality rates, the patient made a full recovery with no complications at discharge or follow-up. This case demonstrates the challenges in treating <i>E. meningoseptica </i>infections and highlights the potential clinical efficacy of antibiotic regimens that may not align with standard susceptibility testing.