Thyroid function status and heterogeneity of efficacy of maintenance cognitive stimulation in late-life dementia: a stratified observational study of subclinical hypothyroidism/hyperthyroidism
MCST improved cognition and reduced caregiver burden over 24 weeks, with smaller benefits in subclinical thyroid dysfunction. Thyroid-aware personalization may better target maintenance cognitive interventions in late-life dementia.
Authors
- Xuebing Xu (ORCID: https://orcid.org/0009-0006-0979-6473)
- S L Wang
- Xiaxia Li
- Yongling Zhou
- Haiyuan Yu
- Bowen Jia
- Xiaomin Yu
- Junhui Yang
- Ling Yang
- Xuan Zhao
- Ruili Zhang
- Feng Li
Institutions
- Ningxia Hui Autonomous Region Peoples Hospital (CN)
- The Fourth People's Hospital of Ningxia Hui Autonomous Region (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-01-12
- DOI
- https://doi.org/10.3389/fneur.2025.1710962
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00