Nephroprotective Effect of L-Carvone on a Mouse Model of LPS-Induced Sepsis-Associated Renal Injury via Regulation of TLR4/NF-κB/AP-1/IRF-3 and Nrf2/iNOS Molecular Signaling Cascades

L-carvone effectively mitigates sepsis-related renal impairment by counteracting inflammatory, oxidative, and apoptotic mechanisms, thus supporting its translational therapeutic promise.

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Publication Details

Journal
Journal of Taibah University Medical Sciences
Published
2026-01-12
DOI
https://doi.org/10.1016/j.jtumed.2025.12.008
Citations
1
Primary Topic
Acute Kidney Injury Research
Type
article
Field-Weighted Citation Impact
34.94
Controls
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article

Nephroprotective Effect of L-Carvone on a Mouse Model of LPS-Induced Sepsis-Associated Renal Injury via Regulation of TLR4/NF-κB/AP-1/IRF-3 and Nrf2/iNOS Molecular Signaling Cascades

Sarmed H. Kathem, Saja Majeed Shareef
1 citations
Journal of Taibah University Medical Sciences
Acute Kidney Injury Research
34.94
article

Nephroprotective Effect of L-Carvone on a Mouse Model of LPS-Induced Sepsis-Associated Renal Injury via Regulation of TLR4/NF-κB/AP-1/IRF-3 and Nrf2/iNOS Molecular Signaling Cascades

Sarmed H. Kathem, Saja Majeed Shareef
article en
1 citations

Abstract

L-carvone effectively mitigates sepsis-related renal impairment by counteracting inflammatory, oxidative, and apoptotic mechanisms, thus supporting its translational therapeutic promise.

Journal of Taibah University Medical SciencesVol. 21(1)
University of Baghdad (IQ), University of Babylon (IQ), Al Mansour University College (IQ)
Good health and well-being
Openalex Percentile: Top 2%
Acute Kidney Injury Research
34.94
DOIOpen Access PDFOpenAlex
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