Dual function antibody targeting αvβ3 and PD-L1 provide a promising strategy for solid tumor therapy

The dual function antibody targeting both αvβ3 and PD-L1 holds the potential to reverse immune evasion and exhibit synergistic anti-tumor effects, offering a promising therapeutic strategy for the treatment of solid tumor.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-12
DOI
https://doi.org/10.3389/fimmu.2025.1691774
Primary Topic
Cell Adhesion Molecules Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Dual function antibody targeting αvβ3 and PD-L1 provide a promising strategy for solid tumor therapy

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Frontiers in Immunology
Cell Adhesion Molecules Research
article

Dual function antibody targeting αvβ3 and PD-L1 provide a promising strategy for solid tumor therapy

Genbei Wang, Huaibin Mu, Ruijia Hao, Guixia Li, Yibo Wang, Xuemin Zheng, Yuxin Bi, Ruijing Huang, Xiaohui Ma, Jian Li, Shuiping Zhou, Liuli Wang, Jin Han, Yanchen Yin, Wenlei Li, Yan Yu
article en

Abstract

The dual function antibody targeting both αvβ3 and PD-L1 holds the potential to reverse immune evasion and exhibit synergistic anti-tumor effects, offering a promising therapeutic strategy for the treatment of solid tumor.

Frontiers in ImmunologyVol. 16
Tasly Holding Group (China) (CN)
Good health and well-being
Openalex Percentile: Top 93%
Cell Adhesion Molecules Research
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