Comparative Analysis of Eye Movement Patterns in Patients with Posttraumatic Stress Disorder and Other Mental Disorders: An Analytical Review of the Literature

In a scientific review, global studies on this issue, covering various nosological groups, were analyzed to determine the similarities and differences in oculomotor biomarkers of mental disorders: posttraumatic stress disorder (PTSD), depressive disorder, bipolar disorder, obsessive-compulsive disorder, generalized anxiety disorder (GAD), personality disorders, and schizophrenia. The analysis showed common features of oculomotor responses associated with impaired inhibitory control of attention processes and amygdala hyperactivity, most pronounced in patients with PTSD and GAD, as well as unique eye movement patterns for each disorder.

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Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2025-12-30
DOI
https://doi.org/10.17116/jnevro202512512136
Primary Topic
Posttraumatic Stress Disorder Research
Type
article
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article

Comparative Analysis of Eye Movement Patterns in Patients with Posttraumatic Stress Disorder and Other Mental Disorders: An Analytical Review of the Literature

AS Chausov, E.Yu. Shelepin, V.M. Zubko, K.A. Skuratova et al.
S S Korsakov Journal of Neurology and Psychiatry
Posttraumatic Stress Disorder Research
article

Comparative Analysis of Eye Movement Patterns in Patients with Posttraumatic Stress Disorder and Other Mental Disorders: An Analytical Review of the Literature

AS Chausov, E.Yu. Shelepin, V.M. Zubko, K.A. Skuratova, K.Yu. Shelepin
article en

Abstract

In a scientific review, global studies on this issue, covering various nosological groups, were analyzed to determine the similarities and differences in oculomotor biomarkers of mental disorders: posttraumatic stress disorder (PTSD), depressive disorder, bipolar disorder, obsessive-compulsive disorder, generalized anxiety disorder (GAD), personality disorders, and schizophrenia. The analysis showed common features of oculomotor responses associated with impaired inhibitory control of attention processes and amygdala hyperactivity, most pronounced in patients with PTSD and GAD, as well as unique eye movement patterns for each disorder.

S S Korsakov Journal of Neurology and PsychiatryVol. 125(12)
Alzheimer’s Disease Neuroimaging Initiative (US), Pavlov Institute of Physiology of the Russian Academy of Sciences (RU), Federal Medical Research Centre for Psychiatry and Narcology (RU)
Openalex Percentile: Top 24%
Posttraumatic Stress Disorder Research
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