Multimodal imaging findings of primary renal well-differentiated neuroendocrine tumors (carcinoid): a case report and literature review

Primary renal well-differentiated neuroendocrine tumors (NETs) are rare. Due to their non-specific nature, the detection and monitoring of NETs remain highly challenging. Here, we report a case of a 45-year-old man who was admitted after an incidental finding of a space-occupying lesion in the kidney during a routine physical examination. The patient underwent CT and MRI multimodal imaging, followed by pathological and immunohistochemical analysis after surgery, leading to a diagnosis of well-differentiated renal NET. He was subsequently followed up for a long period. A review of the literature, in conjunction with this case, revealed that these tumors present with non-specific clinical and imaging features. Diagnosis primarily relies on pathological and immunohistochemical evaluation. Well-differentiated renal neuroendocrine tumors are associated with low malignant potential and a favorable prognosis. Surgical resection is the treatment of choice, and long-term follow-up is essential to monitor the patient's condition. By combining this case with existing literature, we aim to provide valuable insights for clinicians in the diagnosis and management of renal NETs.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-12
DOI
https://doi.org/10.3389/fonc.2025.1597024
Primary Topic
Neuroendocrine Tumor Research Advances
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article
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article

Multimodal imaging findings of primary renal well-differentiated neuroendocrine tumors (carcinoid): a case report and literature review

Bangcheng Wei, Shuai Zhang, Yuge Chen, Yuge Chen
Frontiers in Oncology
Neuroendocrine Tumor Research Advances
article

Multimodal imaging findings of primary renal well-differentiated neuroendocrine tumors (carcinoid): a case report and literature review

Bangcheng Wei, Shuai Zhang, Yuge Chen, Yuge Chen
article en

Abstract

Primary renal well-differentiated neuroendocrine tumors (NETs) are rare. Due to their non-specific nature, the detection and monitoring of NETs remain highly challenging. Here, we report a case of a 45-year-old man who was admitted after an incidental finding of a space-occupying lesion in the kidney during a routine physical examination. The patient underwent CT and MRI multimodal imaging, followed by pathological and immunohistochemical analysis after surgery, leading to a diagnosis of well-differentiated renal NET. He was subsequently followed up for a long period. A review of the literature, in conjunction with this case, revealed that these tumors present with non-specific clinical and imaging features. Diagnosis primarily relies on pathological and immunohistochemical evaluation. Well-differentiated renal neuroendocrine tumors are associated with low malignant potential and a favorable prognosis. Surgical resection is the treatment of choice, and long-term follow-up is essential to monitor the patient's condition. By combining this case with existing literature, we aim to provide valuable insights for clinicians in the diagnosis and management of renal NETs.

Frontiers in OncologyVol. 15
Affiliated Hospital of Jining Medical University (CN), Jining Medical University (CN)
Good health and well-being
Openalex Percentile: Top 91%
Neuroendocrine Tumor Research Advances
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Multimodal imaging findings of primary renal well-differentiated neuroendocrine tumors (carcinoid): a case report and literature review — Bangcheng Wei, Shuai Zhang, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS