ScRNA-seq Identifies High CXCL8 Linked to Liver Fibrosis in HBeAg-negative Chronic Hepatitis B Patients With Low HBsAg
Elevated CXCL8 expression in plasma, peripheral, and intrahepatic mono-mac populations, along with distinct CD8 T-cell clusters, is associated with greater fibrosis in patients with low HBsAg levels.
Authors
- Gayatri Ramakrishna (ORCID: https://orcid.org/0000-0003-4345-294X)
- Pramod Sharma Gautam (ORCID: https://orcid.org/0000-0002-0599-6439)
- Archana Rastogi
- Ravinder Singh
- Shiv Kumar Sarin
- Nirupama Trehanpati
- Manoj Kumar Sharma
Institutions
- Institute of Liver and Biliary Sciences (IN)
Publication Details
- Journal
- Gastro Hep Advances
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.gastha.2026.100880
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00