Serum cytokines predict response and survival in esophageal squamous cell carcinoma receiving chemoradiotherapy combined with anti-PD-1 antibody: analyses of two phase II clinical trials
The CYTOscore based on IL-8, CCL3, and CCL4 effectively predicts treatment response and survival in ESCC patients receiving CRT plus anti-PD-1 antibody.
Authors
- Z. Li
- K. Kalyani Bai (ORCID: https://orcid.org/0000-0001-5481-0322)
- Sifen Wang
- Yi Chen (ORCID: https://orcid.org/0000-0002-4891-8289)
- Tao Yang (ORCID: https://orcid.org/0000-0002-6197-1391)
- Mian Xi (ORCID: https://orcid.org/0000-0002-1452-7968)
- Yilu Gao
- Baoqing Chen (ORCID: https://orcid.org/0000-0001-6367-2558)
- Biqi Chen
- Yujia Zhu
- Peiying Cen
- Xingyuan Cheng
- Ruixi Wang
- Junying Chen
- Shuangjiang Li
- Qiaoqiao Li
Institutions
- Sun Yat-sen University (CN)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- Humboldt-Universität zu Berlin (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Sun Yat-sen University Cancer Center (CN)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1136/jitc-2025-013065
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- Deutschen Konsortium für Translationale Krebsforschung
- Berlin Institute of Health
- Sun Yat-sen University Cancer Center
- Basic and Applied Basic Research Foundation of Guangdong Province