Radiological and Histopathological Predictors of Survival in Neuroendocrine Differentiated Breast Cancer: A Comparative Analysis with NS-IDC

Although NEBC exhibits distinct MRI characteristics and a predominantly hormone-positive IHC profile, survival outcomes were comparable to those of NS-IDC. Notably, T2 hyperintensity on MRI was the strongest imaging feature associated with poorer survival, suggesting a potential role in future prognostic stratification. The modest sample size, prognostic interpretations should be viewed as exploratory. Larger prospective studies are needed to validate these findings.

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Publication Details

Journal
Breast Cancer Targets and Therapy
Published
2026-01-01
DOI
https://doi.org/10.2147/bctt.s569083
Primary Topic
Breast Lesions and Carcinomas
Type
article
Field-Weighted Citation Impact
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article

Radiological and Histopathological Predictors of Survival in Neuroendocrine Differentiated Breast Cancer: A Comparative Analysis with NS-IDC

Levent Altın, Nebil Havvat, Zehra Adibelli, Ahmet Bozer et al.
Breast Cancer Targets and Therapy
Breast Lesions and Carcinomas
article

Radiological and Histopathological Predictors of Survival in Neuroendocrine Differentiated Breast Cancer: A Comparative Analysis with NS-IDC

Levent Altın, Nebil Havvat, Zehra Adibelli, Ahmet Bozer, Demet Kocatepe Çavdar, Hülya Çetin Tunçez
article en

Abstract

Although NEBC exhibits distinct MRI characteristics and a predominantly hormone-positive IHC profile, survival outcomes were comparable to those of NS-IDC. Notably, T2 hyperintensity on MRI was the strongest imaging feature associated with poorer survival, suggesting a potential role in future prognostic stratification. The modest sample size, prognostic interpretations should be viewed as exploratory. Larger prospective studies are needed to validate these findings.

Breast Cancer Targets and TherapyVol. Volume 18
Izmir University (TR), Sağlık Bilimleri Üniversitesi (TR)
No poverty
Openalex Percentile: Top 91%
Breast Lesions and Carcinomas
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Radiological and Histopathological Predictors of Survival in Neuroendocrine Differentiated Breast Cancer: A Comparative Analysis with NS-IDC — Levent Altın, Nebil Havvat, et al. · Breast Cancer Targets and Therapy (2026) | TGRS Research Map | TGRS