A Sheep in Wolf\'s Clothing—The Enigmatic Uterine Giant: A Surgical Dilemma in a Perimenopausal Woman

Gestational trophoblastic disease (GTD) encompasses a spectrum of disorders ranging from benign hydatidiform mole to malignant choriocarcinoma.Diagnosis is often straightforward, but atypical presentations may mimic other uterine malignancies, creating diagnostic and therapeutic dilemmas.We present a rare case of a perimenopausal woman with a large intrauterine mass, markedly elevated serum -hCG, and an inconclusive preoperative biopsy, who underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy (TLH-BSO).Histopathology confirmed a complete hydatidiform mole (CHM).This case highlights the importance of individualized surgical decision-making in atypical GTD presentations.

Authors

Publication Details

Journal
Journal of South Asian Federation of Obstetrics and Gynaecology
Published
2026-01-08
DOI
https://doi.org/10.5005/jp-journals-10006-2825
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
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article

A Sheep in Wolf\'s Clothing—The Enigmatic Uterine Giant: A Surgical Dilemma in a Perimenopausal Woman

Niranjana Jayakrishnan, Ruchika Garg, Kokila Nishanth, Geetanjali Sharma
Journal of South Asian Federation of Obstetrics and Gynaecology
Uterine Myomas and Treatments
article

A Sheep in Wolf\'s Clothing—The Enigmatic Uterine Giant: A Surgical Dilemma in a Perimenopausal Woman

Niranjana Jayakrishnan, Ruchika Garg, Kokila Nishanth, Geetanjali Sharma
article en

Abstract

Gestational trophoblastic disease (GTD) encompasses a spectrum of disorders ranging from benign hydatidiform mole to malignant choriocarcinoma.Diagnosis is often straightforward, but atypical presentations may mimic other uterine malignancies, creating diagnostic and therapeutic dilemmas.We present a rare case of a perimenopausal woman with a large intrauterine mass, markedly elevated serum -hCG, and an inconclusive preoperative biopsy, who underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy (TLH-BSO).Histopathology confirmed a complete hydatidiform mole (CHM).This case highlights the importance of individualized surgical decision-making in atypical GTD presentations.

Journal of South Asian Federation of Obstetrics and GynaecologyVol. 17(6)
Gender equality
Openalex Percentile: Top 92%
Uterine Myomas and Treatments
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