Elucidating the molecular mechanisms of perfluorodecanoic acid and perfluorooctane sulfonic acid on glioblastoma through network toxicology and bioinformatics
This study combined bioinformatics and network toxicology analysis strategies to identified hub genes potentially mediating the effects of PFDA/PFOS, providing evidences that PFDA/PFOS exposure have a potential association with GBM prognosis. Our study emphasized the need for further epidemiological and clinical studies.
Authors
- Taoliang Chen (ORCID: https://orcid.org/0000-0003-1213-1684)
- Hao Liang (ORCID: https://orcid.org/0000-0002-6851-8418)
- Xinlin Sun
- Qinhong Huang
Institutions
- Online Technologies (United States) (US)
- Zhujiang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1097/js9.0000000000003890
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 0.00