Actionable genomic landscape of biliary tract cancer in the Indian population

This study provides a comprehensive molecular profiling of BTCs in the Indian population, revealing key genomic alterations, subtype-specific differences, and associations with immune features. The findings underscore the importance of molecular profiling in guiding personalized treatment strategies.

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Publication Details

Journal
The Oncologist
Published
2026-01-08
DOI
https://doi.org/10.1093/oncolo/oyaf430
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Actionable genomic landscape of biliary tract cancer in the Indian population

Damian Tobias Rieke, Rajan Datar, Darshit Shah, Janani Sambath et al.
The Oncologist
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Actionable genomic landscape of biliary tract cancer in the Indian population

Damian Tobias Rieke, Rajan Datar, Darshit Shah, Janani Sambath, Andrew Gaya, Senthil Jagannathan Rajappa, Aditya Shreenivas, Chetan Madre, Nitesh Rohatgi, Soumil Vyas, Irene A. George, Darshana Patil, Niyati Shah, Pritam Kataria, Ashok K. Vaid, Ruturaj Deshpande, Anjali Parab, Shambhavi Singh, Shriniwas Kulkarni, Prashant Kumar, Aakriti Datta, Humaid Al Shamsi, Milind M. Javle, Sewanti Limaye
article en

Abstract

This study provides a comprehensive molecular profiling of BTCs in the Indian population, revealing key genomic alterations, subtype-specific differences, and associations with immune features. The findings underscore the importance of molecular profiling in guiding personalized treatment strategies.

The OncologistVol. 31(3)
The University of Texas MD Anderson Cancer Center (US), Indian Institute of Technology Bombay (IN), Manipal Academy of Higher Education (IN), Guy's and St Thomas' NHS Foundation Trust (GB), Sir H.N. Reliance Foundation Hospital and Research Centre (IN), Research Medical Center (US), Humboldt-Universität zu Berlin (DE), Basavatarakam Indo American Cancer Hospital and Research Institute (IN), Fortis Memorial Research Institute (IN), City of Hope (US), Medanta The Medicity (IN), Cancer Hospital and Research Institute (IN), Mediclinic City Hospital (AE), Datar Cancer Genetics (India) (IN), Institute of Bioinformatics (IN), Sahyadri Hospital (IN)
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Openalex Percentile: Top 92%
Cholangiocarcinoma and Gallbladder Cancer Studies
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