Intravitreal Ranibizumab versus Vitreous Lavage for Postoperative Vitreous Hemorrhage in Proliferative Diabetic Retinopathy: A Randomized Controlled Trial

VL and IVR were both associated with improved visual outcomes in patients with POVH throughout the 24-week follow-up period. The VL group achieved immediate BCVA improvement, and IVR showed a progressive improvement pattern. The VL group showed superior short-term efficiency. IVR showed a trend towards sustained recovery over the 24-week study period. In our study, IVR showed a trend of higher recovery efficiency within the follow-up timeframe. The advert treatment outcomes after the two treatments did not significantly differ. Thus, treatment selection should balance the urgency of visual rehabilitation and patient-specific factors.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2026-01-01
DOI
https://doi.org/10.2147/dddt.s557400
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Intravitreal Ranibizumab versus Vitreous Lavage for Postoperative Vitreous Hemorrhage in Proliferative Diabetic Retinopathy: A Randomized Controlled Trial

W Li, Bojie Hu, Yue Pan, Jiaxing Chi et al.
Drug Design Development and Therapy
Retinal Diseases and Treatments
article

Intravitreal Ranibizumab versus Vitreous Lavage for Postoperative Vitreous Hemorrhage in Proliferative Diabetic Retinopathy: A Randomized Controlled Trial

W Li, Bojie Hu, Yue Pan, Jiaxing Chi, Xiang Zhang, Zetong Nie
article en

Abstract

VL and IVR were both associated with improved visual outcomes in patients with POVH throughout the 24-week follow-up period. The VL group achieved immediate BCVA improvement, and IVR showed a progressive improvement pattern. The VL group showed superior short-term efficiency. IVR showed a trend towards sustained recovery over the 24-week study period. In our study, IVR showed a trend of higher recovery efficiency within the follow-up timeframe. The advert treatment outcomes after the two treatments did not significantly differ. Thus, treatment selection should balance the urgency of visual rehabilitation and patient-specific factors.

Drug Design Development and TherapyVol. Volume 20
Tianjin Medical University Eye Hospital (CN), Tianjin Medical University (CN)
Natural Science Foundation of Tianjin City
Good health and well-being
Openalex Percentile: Top 91%
Retinal Diseases and Treatments
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Intravitreal Ranibizumab versus Vitreous Lavage for Postoperative Vitreous Hemorrhage in Proliferative Diabetic Retinopathy: A Randomized Controlled Trial — W Li, Bojie Hu, et al. · Drug Design Development and Therapy (2026) | TGRS Research Map | TGRS