The role of the duration of untreated illness (DUI) in generalized anxiety disorder: a cross-sectional, multicenter study

Our findings suggest that reducing the time between the onset of GAD and the initiation of appropriate pharmacological treatment may improve clinical outcomes, mitigating the risk of a chronic course of illness. Further studies are needed to elucidate the role of DUI as a prognostic factor in GAD.

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Publication Details

Journal
CNS Spectrums
Published
2026-01-01
DOI
https://doi.org/10.1017/s1092852925100758
Primary Topic
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Type
article
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article

The role of the duration of untreated illness (DUI) in generalized anxiety disorder: a cross-sectional, multicenter study

Enrico Capuzzi, Fabrizia Colmegna, Davide La Tegola, Letizia Maria Affaticati et al.
CNS Spectrums
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
article

The role of the duration of untreated illness (DUI) in generalized anxiety disorder: a cross-sectional, multicenter study

Enrico Capuzzi, Fabrizia Colmegna, Davide La Tegola, Letizia Maria Affaticati, Elisa Giglio, Irene Riva
article en

Abstract

Our findings suggest that reducing the time between the onset of GAD and the initiation of appropriate pharmacological treatment may improve clinical outcomes, mitigating the risk of a chronic course of illness. Further studies are needed to elucidate the role of DUI as a prognostic factor in GAD.

CNS SpectrumsVol. 31(1)
University of Milan (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Milano-Bicocca (IT)
No poverty
Openalex Percentile: Top 92%
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
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The role of the duration of untreated illness (DUI) in generalized anxiety disorder: a cross-sectional, multicenter study — Enrico Capuzzi, Fabrizia Colmegna, et al. · CNS Spectrums (2026) | TGRS Research Map | TGRS