Assessing Retinal Thickness and Associations with Cognitive Function in Women with History of Preeclampsia

Our study provides a novel, integrated assessment of preeclampsia by simultaneously evaluating retina and cognitive markers. Retinal imaging 10-15 years after delivery in women with a history of preeclampsia showed a decreased thickness in the outer region of the retina. Selective vulnerability of peripheral retinal regions to persistent microvascular changes after preeclampsia may reflect broader central nervous system changes associated with impairments in information processing speed, executive functioning and working memory.

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Publication Details

Journal
Eye and Brain
Published
2026-01-01
DOI
https://doi.org/10.2147/eb.s542082
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Assessing Retinal Thickness and Associations with Cognitive Function in Women with History of Preeclampsia

Meryl A. Butters, Silverstein Sm, Andrea J. Ibarra, BaDoi Phan et al.
Eye and Brain
Pregnancy and preeclampsia studies
article

Assessing Retinal Thickness and Associations with Cognitive Function in Women with History of Preeclampsia

Meryl A. Butters, Silverstein Sm, Andrea J. Ibarra, BaDoi Phan, Janet Catov, Ethan Rossi, Valerie Snyder
article en

Abstract

Our study provides a novel, integrated assessment of preeclampsia by simultaneously evaluating retina and cognitive markers. Retinal imaging 10-15 years after delivery in women with a history of preeclampsia showed a decreased thickness in the outer region of the retina. Selective vulnerability of peripheral retinal regions to persistent microvascular changes after preeclampsia may reflect broader central nervous system changes associated with impairments in information processing speed, executive functioning and working memory.

Eye and BrainVol. Volume 18
University of Pittsburgh (US), University of Rochester Medical Center (US), Magee-Womens Research Institute (US), University of Pittsburgh Medical Center (US), Stanford Medicine (US)
American Heart Association, Research to Prevent Blindness, Foundation for Anesthesia Education and Research, University of Pittsburgh, Jewish Healthcare Foundation, National Institutes of Health
Gender equality
Openalex Percentile: Top 92%
Pregnancy and preeclampsia studies
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Assessing Retinal Thickness and Associations with Cognitive Function in Women with History of Preeclampsia — Meryl A. Butters, Silverstein Sm, et al. · Eye and Brain (2026) | TGRS Research Map | TGRS