A Rare Case of Gluteal Compartment Syndrome and Rhabdomyolysis After Robotic-Assisted Partial Nephrectomy

Gluteal compartment syndrome (GCS) is a rare but serious condition involving high intra-compartmental pressures that can result in rhabdomyolysis with tissue ischemia and necrosis. We present the case of a 38-year-old male with class III obesity who was positioned in lateral decubitus for a 4-h long robotic-assisted partial nephrectomy, completed in standard transperitoneal fashion, for a 3-cm renal mass later diagnosed as renal cell carcinoma, chromophobe type. Postoperatively, patient demonstrated clinical picture consistent with GCS, including pain with passive motion, weakness, tea-colored urine, and elevated creatine kinase (CK). He was managed expeditiously with emergent gluteal fasciotomy. Postoperatively, his CK and pain improved and he was discharged on postoperative day 5. At 1-year follow-up, he has normal renal function, no evidence of renal cell carcinoma (RCC) recurrence, and normal neurologic and muscle function. His case demonstrates the need for a high index of suspicion for musculoskeletal complications when operating on severely obese patients.

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Publication Details

Journal
World Journal of Nephrology and Urology
Published
2026-01-01
DOI
https://doi.org/10.14740/wjnu1007
Primary Topic
Muscle and Compartmental Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

A Rare Case of Gluteal Compartment Syndrome and Rhabdomyolysis After Robotic-Assisted Partial Nephrectomy

Alyssa Lombardo, Dan Li, Hannah Harris, Daniel A. Evans et al.
World Journal of Nephrology and Urology
Muscle and Compartmental Disorders
article

A Rare Case of Gluteal Compartment Syndrome and Rhabdomyolysis After Robotic-Assisted Partial Nephrectomy

Alyssa Lombardo, Dan Li, Hannah Harris, Daniel A. Evans, Julie Bishop, Eric A. Singer
article en

Abstract

Gluteal compartment syndrome (GCS) is a rare but serious condition involving high intra-compartmental pressures that can result in rhabdomyolysis with tissue ischemia and necrosis. We present the case of a 38-year-old male with class III obesity who was positioned in lateral decubitus for a 4-h long robotic-assisted partial nephrectomy, completed in standard transperitoneal fashion, for a 3-cm renal mass later diagnosed as renal cell carcinoma, chromophobe type. Postoperatively, patient demonstrated clinical picture consistent with GCS, including pain with passive motion, weakness, tea-colored urine, and elevated creatine kinase (CK). He was managed expeditiously with emergent gluteal fasciotomy. Postoperatively, his CK and pain improved and he was discharged on postoperative day 5. At 1-year follow-up, he has normal renal function, no evidence of renal cell carcinoma (RCC) recurrence, and normal neurologic and muscle function. His case demonstrates the need for a high index of suspicion for musculoskeletal complications when operating on severely obese patients.

World Journal of Nephrology and UrologyVol. 15(1)
The Ohio State University Wexner Medical Center (US)
National Cancer Institute
Good health and well-being
Openalex Percentile: Top 92%
Muscle and Compartmental Disorders
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A Rare Case of Gluteal Compartment Syndrome and Rhabdomyolysis After Robotic-Assisted Partial Nephrectomy — Alyssa Lombardo, Dan Li, et al. · World Journal of Nephrology and Urology (2026) | TGRS Research Map | TGRS