Adrenal insufficiency following systemic glucocorticoid therapy: a systematic review and meta-analysis
AI is frequent following systemic GC use, with considerable variability. Tapering regimens and delayed testing post-cessation appear to reduce the observed prevalence. No specific GC regimen reliably prevents AI.
Authors
- Fiona Pearce (ORCID: https://orcid.org/0000-0003-2884-1998)
- S. Lax (ORCID: https://orcid.org/0000-0002-7000-9364)
- Sophie Shallish
- Jonathan Bowley
- Natasha Smyth
Institutions
- North Bristol NHS Trust (GB)
- Nottingham University Hospitals NHS Trust (GB)
- University of Nottingham (GB)
- Southmead Hospital (GB)
- Queen's Medical Centre (GB)
- Great Western Hospitals NHS Foundation Trust (GB)
Publication Details
- Journal
- European Journal of Internal Medicine
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.ejim.2026.106707
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research