Agreement between Alzheimer's disease blood biomarkers and clinical diagnosis in primary care

These are the first results of the ongoing CANTATE-PC study. Our findings indicate a high agreement between possible cognitive impairment as indicated by a MoCA score <26 and a syndrome diagnosis of MCI or dementia in primary care, but a low agreement between GPs' etiological diagnosis and abnormal AD blood biomarkers in this group. Our results suggest that AD blood biomarkers may be able to offer additional support to GPs when evaluating the presence of AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_105489
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Agreement between Alzheimer's disease blood biomarkers and clinical diagnosis in primary care

Melchior C. Nierman, Thomas Claessen, Jurgen Kooren, Michelle Barboure et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Agreement between Alzheimer's disease blood biomarkers and clinical diagnosis in primary care

Melchior C. Nierman, Thomas Claessen, Jurgen Kooren, Michelle Barboure, Inge M.W. Verberk, W. M. van der Flier, David H Wilson, Charlotte E. Teunissen, Argonde C. van Harten
article en

Abstract

These are the first results of the ongoing CANTATE-PC study. Our findings indicate a high agreement between possible cognitive impairment as indicated by a MoCA score <26 and a syndrome diagnosis of MCI or dementia in primary care, but a low agreement between GPs' etiological diagnosis and abnormal AD blood biomarkers in this group. Our results suggest that AD blood biomarkers may be able to offer additional support to GPs when evaluating the presence of AD.

Alzheimer s & DementiaVol. 21(S2)
Amsterdam Neuroscience (NL), Quanterix (United States) (US), Amsterdam University Medical Centers (NL)
Openalex Percentile: Top 28%
Dementia and Cognitive Impairment Research
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Agreement between Alzheimer's disease blood biomarkers and clinical diagnosis in primary care — Melchior C. Nierman, Thomas Claessen, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS