Ease of Undergoing Laparoscopic Cholecystectomy under Spinal Anaesthesia in Male versus Female Patients

Abstract Background: Laparoscopic cholecystectomy under spinal anaesthesia is a safe and effective alternative to general anaesthesia. However, little is known about the impact of gender on outcomes following LC under SA. Methods: This single-centre study compared intraoperative and postoperative outcomes between male and female patients undergoing elective LC under SA. In the study, 47 male and 92 female patients were analysed. Outcomes included operative time, conversion to GA, intraoperative complications (hypotension, bradycardia, shoulder pain), postoperative pain scores, nausea/vomiting, and length of stay. Statistical analysis was performed using appropriate tests (t-tests, chi-square tests, and Mann-Whitney U tests) with a significance level of p < 0.05. Results: It was observed that male patients had significantly longer operative times (65.6 ± 15.1 min vs. 57.6 ± 12.3 min, p = 0.04) and a higher conversion rate to GA (17.0% vs. 5.4%, p = 0.02) compared to female patients. There were no significant differences in other intraoperative complications, postoperative pain scores, nausea/vomiting, or LOS. Conclusions: The study concluded that male gender was associated with longer operative times and a higher risk of conversion to GA during LC under SA. Further research is needed to explore the underlying reasons for these differences and to optimize outcomes in male patients.