Defining regional tau‐PET positivity cut points in atypical AD
Tau uptake in temporal regions showed the greatest group-level differentiation. However, examining regional tau-positivity may offer better sensitivity in atypical AD patients compared to the temporal meta-ROI, likely due to the presence of focal non-temporal patterns of uptake.
Authors
- Stephen D. Weigand (ORCID: https://orcid.org/0000-0002-4541-9011)
- Amanda L. Tapia (ORCID: https://orcid.org/0000-0001-7348-7372)
- VJ Lowe (ORCID: https://orcid.org/0000-0002-5612-1667)
- Neha Singh‐Reilly
- Jennifer L. Whitwell
- Ryota Satoh
- Christopher G Schwarz
- Jonathan Graff‐Radford
- Clifford R. Jack
- Mary M. Machulda
- Keith A. Josephs
Institutions
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_106619
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00