Microstructural and Water Exchange Alterations in ARIA‐E in a Real‐World Cohort Receiving Anti‐Amyloid Therapy
Measures of water diffusion and exchange enhance our understanding of ARIA with findings consistent with transient increases in cellularity at ARIA onset and prolonged increases in parenchymal water permeability and edema. Early results suggest microstructure could predict risk for future ARIA. Additional data collection continues.
Authors
- David C. Alsop (ORCID: https://orcid.org/0000-0002-8206-1995)
- Emily McGrew
- Danielle Hing
- Dawn Mechanic‐Hamilton
- David A. Wolk
- Paul A. Yushkevich
- Manuel Taso
- John A. Detre
- Christopher A Brown
- Ilya M. Nasrallah
- Sandhitsu R. Das
Institutions
- Beth Israel Deaconess Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_107657
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00