Longitudinal analysis of plasma <i>p</i> ‐Tau181 in African and African American populations from the Indianapolis‐Ibadan Dementia Cohort

While geographic location has been seen to influence APOE genotype risk, similar investigations of AD biomarkers has been limited. Our data suggest there are differences in etiology that drives cognitive impairment between the African Americans in Indianapolis and the Africans in Ibadan. Additional analyses must be done to determine what drives these differences and the most effective biomarkers or biomarker combinations for differing populations.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_107656
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal analysis of plasma p ‐Tau181 in African and African American populations from the Indianapolis‐Ibadan Dementia Cohort

L. Dage Jeffrey, Kathleen A. Lane, Kristen A. Russ, Hugh C. Hendrie et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Longitudinal analysis of plasma p ‐Tau181 in African and African American populations from the Indianapolis‐Ibadan Dementia Cohort

L. Dage Jeffrey, Kathleen A. Lane, Kristen A. Russ, Hugh C. Hendrie, Sujuan Gao, Tatiana M. Foroud, Frederick W. Unverzagt
article en

Abstract

While geographic location has been seen to influence APOE genotype risk, similar investigations of AD biomarkers has been limited. Our data suggest there are differences in etiology that drives cognitive impairment between the African Americans in Indianapolis and the Africans in Ibadan. Additional analyses must be done to determine what drives these differences and the most effective biomarkers or biomarker combinations for differing populations.

Alzheimer s & DementiaVol. 21(S2)
Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Openalex Percentile: Top 28%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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