Rapid profiling of polymyxin B susceptibility in Gram-negative bacteria with a novel polymyxin-derived fluorescent probe
The RAPID<sub>FC</sub> method, based on the polymyxin-derived fluorescent probe, is fast and applicable to multiple species, making it a promising antimicrobial susceptibility method to guide appropriate therapy in the clinic. The case ofA. baumanniidemonstrates that species-specific resistance mechanisms may require tailored optimization of detection protocols.
Authors
- Maite Amado (ORCID: https://orcid.org/0000-0002-6309-3852)
- Sanjaya KC (ORCID: https://orcid.org/0000-0002-4779-3066)
- Mark A. T. Blaskovich (ORCID: https://orcid.org/0000-0001-9447-2292)
- Ruby Pelingon (ORCID: https://orcid.org/0000-0001-7295-088X)
- Alysha G. Elliott (ORCID: https://orcid.org/0000-0002-2983-0484)
- Alejandra Gallardo-Godoy
- Matthew A. Cooper
- Wanida Phetsang
- Mark S. Butler
- Bing Zhang
Institutions
- The University of Queensland (AU)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.jare.2026.01.019
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00