Decreased Audio‐Visual Network Integration Mediates Amyloid‐related Tau Spreading

Our study suggests that audio-visual network integration during the early stages of tau pathology mediates amyloid-related tau accumulation. This supports a framework in which decline brain network integration may facilitates the early spread of amyloid-driven tau pathology across interconnected brain regions.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_105624
Primary Topic
Multisensory perception and integration
Type
article
Field-Weighted Citation Impact
0.00
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article

Decreased Audio‐Visual Network Integration Mediates Amyloid‐related Tau Spreading

Nesrine Rahmouni, Jaime Fernández Arias, Jieying Li, Lin Gan et al.
Alzheimer s & Dementia
Multisensory perception and integration
article

Decreased Audio‐Visual Network Integration Mediates Amyloid‐related Tau Spreading

Nesrine Rahmouni, Jaime Fernández Arias, Jieying Li, Lin Gan, Tevy Chan, Yansheng Zheng, Yi‐Ting Wang, Lydia Trudel, Etienne Aumont, Arthur Macedo, Rong Li, Delphine Olivia‐Lopez, Joseph Therriault, Kely Monica Quispialaya Socualaya, Gleb Bezgin, Brandon J Hall, Pedro Rosa‐Neto
article en

Abstract

Our study suggests that audio-visual network integration during the early stages of tau pathology mediates amyloid-related tau accumulation. This supports a framework in which decline brain network integration may facilitates the early spread of amyloid-driven tau pathology across interconnected brain regions.

Alzheimer s & DementiaVol. 21(S2)
Montreal Neurological Institute and Hospital (CA), University of Electronic Science and Technology of China (CN), Université du Québec à Montréal (CA), University of Pavia (IT), Douglas Mental Health University Institute (CA), McGill University (CA)
Openalex Percentile: Top 25%
Multisensory perception and integration
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