Effect of image‐processing and statistical harmonization methods on tau PET cognitive group separability for multisite cross‐sectional and longitudinal studies using <sup>18</sup> F‐Flortaucipir PET
PVC of tau PET data may have a greater harmonizing effect on multi-scanner tau PET data than smoothing to a common resolution. The combination of PVC with LongComBat maximizes the ability to detect group differences in longitudinal change of multi-site FTP PET data.
Authors
- DL Tudorascu
- Howard Jay Aizenstein (ORCID: https://orcid.org/0000-0003-4897-6582)
- Suzanne L. Baker (ORCID: https://orcid.org/0000-0003-0209-3127)
- Weiquan Luo
- Davneet S Minhas
- Alzheimer's Disease Neuroimaging Initiative
- Charles M Laymon
Institutions
- Lawrence Berkeley National Laboratory (US)
- University of Pittsburgh (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_107440
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00