Efficacy of Indocyanine Green-Mediated Antimicrobial Photodynamic Therapy as an Adjunct to Scaling and Root Planing on Periodontal Indices and Microbial Load in Chronic Periodontitis: A Systematic Review and Meta-Analysis
Adjunctive ICG-aPDT showed statistically significant but clinically modest improvements in periodontal outcomes, with PPD effects close to a 1-mm interpretive benchmark; however, high heterogeneity and methodological limitations warrant cautious interpretation and further standardized trials.
Authors
- Shima Afrasiabi (ORCID: https://orcid.org/0000-0002-8341-123X)
- Mohadeseh Heidari
- Fatemeh Taziki
- Shima Younespour
- Alireza Hassani
Institutions
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.pdpdt.2026.105336
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00