Safety of Lumbar Punctures in Older Adults in a Longitudinal Cohort Study of Aging and Alzheimer's Disease
Results indicate that cognitive impairment and routine blood work are related to post-LP symptoms and could be helpful in counseling participants on risk of LP side effects. Forthcoming analyses will include additional common LP symptoms (e.g., radicular pain, vasovagal symptoms) and further characterize headache and back pain (e.g., immediately post-procedure versus delayed) in a larger sample, including participants with LPs performed repeatedly longitudinally.
Authors
- Panpan Zhang (ORCID: https://orcid.org/0000-0002-2124-2733)
- Hailey A. Kresge (ORCID: https://orcid.org/0000-0003-0427-7974)
- Amalia Jo Peterson (ORCID: https://orcid.org/0000-0002-7015-7957)
- Lauren R. Samuels (ORCID: https://orcid.org/0000-0002-7273-5626)
- James Eaton (ORCID: https://orcid.org/0000-0003-0010-921X)
- Kimberly R. Pechman (ORCID: https://orcid.org/0000-0003-0596-8064)
- Emily Moore (ORCID: https://orcid.org/0000-0002-4099-157X)
- Dandan Liu
- Angela L. Jefferson
Institutions
- Brigham and Women's Hospital (US)
- Vanderbilt University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_106066
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00