Blood‐based biomarker for identifying post‐mortem confirmed Cerebral Amyloid Angiopathy
Blood-based biomarkers capable of identifying CAA could play an important role in improving treatment outcomes by highlighting ARIA risk prior to treatment initiation. We found that plasma proteins related to inflammation, blood brain barrier dysfunction and cytoskeletal stability were significantly changed in participants with confirmed CAA. Further work will be required to replicate these findings in an independent dataset.
Authors
- Marisa N. Denkinger (ORCID: https://orcid.org/0000-0002-3696-3795)
- Alpana Singh
- Kari Dieckhoff
- James Liu
- Antoine Leuzy
- Alirez Atri
- Geidy E Serrano
- Nicholas J. Ashton
- Thomas G Beach
- Eric M. Reiman
Institutions
- Banner Sun Health Research Institute (US)
- Banner Alzheimer’s Institute
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_105227
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00