Household-level factors and ART adherence among people living with HIV in Cape Town, South Africa: a qualitative study

South Africa has the largest ART programme in the world. ART is provided within the context of the universal test and treat strategy. Sustained high levels of ART adherence are required to ensure viral suppression and prevent ART-drug resistance. However, poor ART adherence remains a challenge in South Africa. While much research has focused on individual - and community-level factors influencing adherence, household-level factors remain under-researched. This study sought to qualitatively examine the role of household-related factors in ART adherence among 15 newly initiated people living with HIV (PLWH) in Cape Town, South Africa. The information-motivation and behavioural skills model and the concept of the HIV competent household provided the conceptual frameworks for the study. Emotional and instrumental support from household members and in particular mothers facilitated adherence. Open HIV dialogue fostered positive health behaviours and ART adherence. Household food insecurity, multimorbidity and busy work schedules both in the absence of household social support hindered ART adherence. Given the significant role of household support, particularly from mothers, in facilitating ART adherence, health facility programmes should aim to involve household members in the treatment of PLWH. This could be facilitated through training community health workers to foster and support HIV competent households.

Authors

Institutions

Publication Details

Journal
AIDS Care
Published
2026-01-09
DOI
https://doi.org/10.1080/09540121.2025.2604603
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Household-level factors and ART adherence among people living with HIV in Cape Town, South Africa: a qualitative study

Lucia Knight, Caroline Masquillier, Lorraine Tanyaradzwa Dube, Edwin Wouters
AIDS Care
HIV/AIDS Research and Interventions
article

Household-level factors and ART adherence among people living with HIV in Cape Town, South Africa: a qualitative study

Lucia Knight, Caroline Masquillier, Lorraine Tanyaradzwa Dube, Edwin Wouters
article en

Abstract

South Africa has the largest ART programme in the world. ART is provided within the context of the universal test and treat strategy. Sustained high levels of ART adherence are required to ensure viral suppression and prevent ART-drug resistance. However, poor ART adherence remains a challenge in South Africa. While much research has focused on individual - and community-level factors influencing adherence, household-level factors remain under-researched. This study sought to qualitatively examine the role of household-related factors in ART adherence among 15 newly initiated people living with HIV (PLWH) in Cape Town, South Africa. The information-motivation and behavioural skills model and the concept of the HIV competent household provided the conceptual frameworks for the study. Emotional and instrumental support from household members and in particular mothers facilitated adherence. Open HIV dialogue fostered positive health behaviours and ART adherence. Household food insecurity, multimorbidity and busy work schedules both in the absence of household social support hindered ART adherence. Given the significant role of household support, particularly from mothers, in facilitating ART adherence, health facility programmes should aim to involve household members in the treatment of PLWH. This could be facilitated through training community health workers to foster and support HIV competent households.

AIDS CareVol. 38(3)
University of Antwerp (BE), University of Cape Town (ZA), University of the Western Cape (ZA)
No poverty
Openalex Percentile: Top 94%
HIV/AIDS Research and Interventions
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Household-level factors and ART adherence among people living with HIV in Cape Town, South Africa: a qualitative study — Lucia Knight, Caroline Masquillier, et al. · AIDS Care (2026) | TGRS Research Map | TGRS