Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen‐Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells
CA can induce breast cancer apoptosis via ROS generation and activation of JNK and p38 phosphorylation. The anti-tumor effect of CA can be assessed using <sup>99m</sup>Tc-CN5DG SPECT imaging.
Authors
- Sha Luan (ORCID: https://orcid.org/0000-0002-7334-0415)
- Peng Fu (ORCID: https://orcid.org/0000-0002-8437-571X)
- Yuying Jiao
- P. Xu
- Xinyu Wang
- Changjiu Zhao
- Yue Gao
Institutions
- Harbin Medical University (CN)
- Fourth Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1002/cam4.71446
- Primary Topic
- Biochemical effects in animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Harbin Medical University
- National Natural Science Foundation of China
- Research and Innovation Foundation