Plumbagin protects rat cortical neurons from mechanical trauma injury-induced apoptosis by inhibiting NOX4/ROS/p38 MAPK pathway.

The present findings illustrate that PLB can alleviate mechanical trauma injury-induced apoptosis by inhibiting the NOX4/ROS/p38 MAPK pathway in primary cortical neurons.

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Journal
PubMed
Published
2026-01-09
DOI
https://doi.org/10.22038/ajp.2025.25704
Primary Topic
Bioactive Compounds and Antitumor Agents
Type
article
Field-Weighted Citation Impact
0.00

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article

Plumbagin protects rat cortical neurons from mechanical trauma injury-induced apoptosis by inhibiting NOX4/ROS/p38 MAPK pathway.

Haitan Fu, Qianrui Zhang, Wenjuan Gong, Feng Cao et al.
PubMed
Bioactive Compounds and Antitumor Agents
article

Plumbagin protects rat cortical neurons from mechanical trauma injury-induced apoptosis by inhibiting NOX4/ROS/p38 MAPK pathway.

Haitan Fu, Qianrui Zhang, Wenjuan Gong, Feng Cao, Tao Wu
article en

Abstract

The present findings illustrate that PLB can alleviate mechanical trauma injury-induced apoptosis by inhibiting the NOX4/ROS/p38 MAPK pathway in primary cortical neurons.

PubMedVol. 15(6)
Wuhan Puai Hospital (CN), Shanghai Ship and Shipping Research Institute (CN), Central Hospital of Wuhan (CN)
Health Commission of Hubei Province
Good health and well-being
Openalex Percentile: Top 92%
Bioactive Compounds and Antitumor Agents
DOIOpen Access PDFOpenAlex
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