Next‐Generation Paradigm in Dental Implants: Mechanistic Insights and Translational Innovations for Oral Rehabilitation

ABSTRACT Dental implants have transmuted restorative dentistry by offering durable, root‐analog surrogates for hypodontia. Their long‐term performance be synchronized on a coordinated interaction of biological, mechanical, and material features, including osseointegration, soft tissue attachment, and biomechanical stability. Recent advancements uncover novelty through the integration of nanotechnology, surface modification, and regenerative strategies. Nano‐engineered surfaces and specialized coatings enhance bone integration and confer antibacterial properties, while additive manufacturing and 3D bioprinting enable to design patient‐specific scaffolds embedded with bioactive agents and stem cells. Such approaches go beyond conventional prosthetic restoration, aiming instead to regenerate native dental structures such as dentin, pulp, and periodontal ligament with both structural precision and functional relevance. By conglomerating the aspects this review critically leverages mechanistic insights with emerging fabrication technologies, surface architectures, and AI‐assisted design frameworks and silhouette translational pathways for next‐generation bio‐integrated dental implants in oral rehabilitation.

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Publication Details

Journal
ChemistrySelect
Published
2026-01-01
DOI
https://doi.org/10.1002/slct.202506527
Primary Topic
Bone Tissue Engineering Materials
Type
article
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0.00
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article

Next‐Generation Paradigm in Dental Implants: Mechanistic Insights and Translational Innovations for Oral Rehabilitation

Nagarjuna Reddy Paluvai, Shreya Palit, Riya Barui, Rakesh Barman et al.
ChemistrySelect
Bone Tissue Engineering Materials
article

Next‐Generation Paradigm in Dental Implants: Mechanistic Insights and Translational Innovations for Oral Rehabilitation

Nagarjuna Reddy Paluvai, Shreya Palit, Riya Barui, Rakesh Barman, D. Chattopadhyay, Aishwarya Saha, Adrija Ghosh, Arbind Prasad, Sriparna De, Sujay Murmu, Sheikh Minhazuddin Haque
article en

Abstract

ABSTRACT Dental implants have transmuted restorative dentistry by offering durable, root‐analog surrogates for hypodontia. Their long‐term performance be synchronized on a coordinated interaction of biological, mechanical, and material features, including osseointegration, soft tissue attachment, and biomechanical stability. Recent advancements uncover novelty through the integration of nanotechnology, surface modification, and regenerative strategies. Nano‐engineered surfaces and specialized coatings enhance bone integration and confer antibacterial properties, while additive manufacturing and 3D bioprinting enable to design patient‐specific scaffolds embedded with bioactive agents and stem cells. Such approaches go beyond conventional prosthetic restoration, aiming instead to regenerate native dental structures such as dentin, pulp, and periodontal ligament with both structural precision and functional relevance. By conglomerating the aspects this review critically leverages mechanistic insights with emerging fabrication technologies, surface architectures, and AI‐assisted design frameworks and silhouette translational pathways for next‐generation bio‐integrated dental implants in oral rehabilitation.

ChemistrySelectVol. 11(2)
University of Calcutta (IN), Babasaheb Bhimrao Ambedkar Bihar University (IN), Ramakrishna Mission Vivekananda Educational and Research Institute (IN), Asian Institute of Public Health (IN), Geological Survey of India (IN)
Openalex Percentile: Top 92%
Bone Tissue Engineering Materials
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Next‐Generation Paradigm in Dental Implants: Mechanistic Insights and Translational Innovations for Oral Rehabilitation — Nagarjuna Reddy Paluvai, Shreya Palit, et al. · ChemistrySelect (2026) | TGRS Research Map | TGRS