Eccrine Clear Cell Hidradenocarcinoma in an Elderly Female: A Rare Case

Abstract An 80 year old female with medical history of non Hodgkin’s lymphoma in remission presented with skin lesion at right suprapubic region with inflammatory papule following tick bite. The lesion progressively enlarged to a hard, mobile 2.5 cm nodule over the course of three years. After surgical excision, on histopathological examination revealed Eccrine clear cell Hidradenocarcinoma. After diagnosis, the patient underwent PET imaging that showed localized metabolic activity at excision site without lymph node involvement or distant metastasis. A repeat wide excision was performed to achieve clear margins. This case emphasizes the importance of vigilance in evaluating evolving skin lesions, especially benign appearance. Eccrine cell Hidradenocarcinoma is a rare and slow growing malignant tumor. The diagnosis is often delayed due to indolent nature and resemblance to benign skin lesions.