Multiscale Dispersion Entropy of Resting‐State EEG in Older Adults with Alzheimer's Dementia, Mild Cognitive Impairment, or remitted Major Depressive Disorder

This study highlights the value of MDE at a short time scale, related to local neuronal activity, to separate individuals with AD vs. MCI vs. HCs. Reduced complexity in these individuals may underlie their cognitive impairment. In contrast, our study suggests that any MDD impact on complexity is likely related to active depressive symptoms.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_105953
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
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article

Multiscale Dispersion Entropy of Resting‐State EEG in Older Adults with Alzheimer's Dementia, Mild Cognitive Impairment, or remitted Major Depressive Disorder

Shekhar Kumar, Mostafa Rostaghi, Hamed Azami, Heather Brooks et al.
Alzheimer s & Dementia
Functional Brain Connectivity Studies
article

Multiscale Dispersion Entropy of Resting‐State EEG in Older Adults with Alzheimer's Dementia, Mild Cognitive Impairment, or remitted Major Depressive Disorder

Shekhar Kumar, Mostafa Rostaghi, Hamed Azami, Heather Brooks, Flint Aj, Nathan Herrmann, Reza Zomorrodi, Benoit H. Mulsant, Corinne E. Fischer, Damien Gallagher, Daniel M. Blumberger, Tarek K Rajji, PACt‐MD Study Group, Linda Mah, Bruce G. Pollock, Mary Pat McAndrews
article en

Abstract

This study highlights the value of MDE at a short time scale, related to local neuronal activity, to separate individuals with AD vs. MCI vs. HCs. Reduced complexity in these individuals may underlie their cognitive impairment. In contrast, our study suggests that any MDD impact on complexity is likely related to active depressive symptoms.

Alzheimer s & DementiaVol. 21(S2)
St. Michael's Hospital (CA), Sunnybrook Health Science Centre (CA), University Health Network (CA), Centre for Addiction and Mental Health (CA), University of Toronto (CA), Toronto Western Hospital (CA), Health Sciences Centre (CA), Baycrest Hospital (CA), Toronto Dementia Research Alliance (CA), Islamic Azad University Semnan (IR), NeuroDevelopment Center (US), Southwestern University (US), The University of Texas Southwestern Medical Center (US), Semnan University (IR)
Openalex Percentile: Top 29%
Functional Brain Connectivity Studies
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