Characterization of the Functional Transient Receptor Potential Vanilloid Channels 1 to 4 in Human Corneal Endothelial Cells
This study confirms TRPV1 to 4 expression, enumerates their distinct localization and colocalization with junction proteins, and their permeability to Ca2+ in hCEs. Taken together, these results suggest a potential role for these channels in maintaining Ca2+ homeostasis and barrier function in these cells.
Authors
- Charanya Ramachandran (ORCID: https://orcid.org/0000-0002-8961-7618)
- Deep Shikha (ORCID: https://orcid.org/0009-0000-8434-9290)
- Jacquelyn Akepogu (ORCID: https://orcid.org/0009-0005-6855-7045)
- Bokara Kiran Kumar
- Chandan Goswami
- Sirisha Senthil
Institutions
- National Institute of Science Education and Research (IN)
- Manipal Academy of Higher Education (IN)
- Centre for Cellular and Molecular Biology (IN)
- L V Prasad Eye Institute (IN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1167/iovs.67.1.20
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hyderabad Eye Research Foundation
- Science and Engineering Research Board