Associations between brain and cognitive resilience, tau load and extent in Alzheimer's disease
Whole Cortex SEOT exhibits a stronger negative correlation with MMSE compared to Whole Cortex MK-6240 SUVR, indicating that SEOT may serve as a more sensitive marker of cognitive decline in Alzheimer's disease and mild cognitive impairment. Further research is needed to validate SEOT's potential as a diagnostic or prognostic biomarker in neurodegenerative conditions.
Authors
- Chris Hsiao (ORCID: https://orcid.org/0009-0009-2062-3516)
- Nesrine Rahmouni
- Wan Lu Jia
- Jaime Fernández Arias (ORCID: https://orcid.org/0000-0002-6810-5920)
- Tevy Chan (ORCID: https://orcid.org/0009-0001-9134-5949)
- Yansheng Zheng
- Yi‐Ting Wang
- Lydia Trudel (ORCID: https://orcid.org/0009-0002-5593-7717)
- Stuart William Mitchell
- Jean‐Paul Soucy
- Arthur Macedo
- Marina P Gonçalves
- Etienne Aumont
- Stijn Servaes
- Joseph Therriault
- Robert Hopewell
- Pedro Rosa‐Neto
- Brandon J Hall
- Paolo Vitali
- Gleb Bezgin
- Kely Monica Quispialaya Socualaya
- Tharick A Pascoal
Institutions
- Universidade Federal de Minas Gerais (BR)
- University of Southern California (US)
- Montreal Neurological Institute and Hospital (CA)
- Université du Québec à Montréal (CA)
- Concordia University (US)
- Douglas Mental Health University Institute (CA)
- Espace pour la vie (CA)
- McGill University Health Centre (CA)
- Jewish General Hospital (CA)
- Cognitive Neuroimaging Lab (FR)
- Hôpital Sahloul (TN)
- McGill University (CA)
- Concordia University (CA)
- Université de Montréal (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_107705
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00