Spectrum of Thymic Neoplasms in A Tertiary Care Hospital

Introduction The thymus is a primary lymphoid organ of the immune system located in mediastinum. It undergoes several changes as a result of various factors like ageing and medical disorders 1. Thymic neoplasms constitute a rare group of anterior mediastinal mass which shows heterogeneity in clinical presentation and histologic appearance. Most patients with thymic tumors are asymptomatic at the time of diagnosis. Even though diagnosis can be made by clinical course and radiology, biopsy followed by histopathology remains the gold standard for the diagnosis. Now a day, Immunohistochemistry (IHC) is used as a criteria for diagnosis of thymic neoplasms with ambiguous histology2. Materials and Methods This is a 6 year retrospective study conducted in the Department of pathology on resected and biopsy specimens of thymic neoplasms from 2017 to 2023. The present study includes 25 cases of thymic neoplasms. Request forms of the cases were retrieved from the archives to collect available clinical details such as age, gender, symptoms and size of the lesion. All the microscopic slides were retrieved from the archives and reviewed. IHCs were done in 6 cases. Findings were noted in Microsoft excel and analyzed using SPSS V.25.