Validation of the ICD-10 Diagnoses of Early-Onset Neonatal Infection in the Danish National Patient Register from 2010 to 2018

We found a poor validity for the ICD10 diagnoses of early-onset neonatal infection in the Danish National Patient Register. This highlights that the diagnoses should be used cautiously in future research and surveillance and emphasises the need for supporting information on microbiological samples. Additionally, this highlights the importance of establishing a consensus definition of neonatal sepsis to improve diagnostic accuracy.