Peripheral blood immunophenotypic diversity in patients with anti-MDA5+ dermatomyositis and its impact on prognosis
Lymphocytes and their subsets were significantly altered in anti-MDA5+ DM patients. There was remarkable heterogeneity of lymphocyte subsets in anti-MDA5+ DM patients between survivors and non-survivors. Anti-MDA5+ DM patients were divided into two groups with distinct symptoms and survival rate by cluster analysis based on lymphocyte subsets.
Authors
- P W Zhang
- T F Li
- Yujie He
- Yusheng Zhang (ORCID: https://orcid.org/0000-0001-5977-4842)
- Rui Liu (ORCID: https://orcid.org/0009-0002-3689-4061)
- Shengyun Liu (ORCID: https://orcid.org/0000-0003-3197-3158)
- J J Sun
- Wenlu Hu
- Wenjuan Guan
- Chaofeng Lian
- Lijuan Zhang
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Clinical and Experimental Rheumatology
- Published
- 2025-05-04
- DOI
- https://doi.org/10.55563/clinexprheumatol/qumg88
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhengzhou University
- Natural Science Foundation of Henan Province
- First Affiliated Hospital of Zhengzhou University