Advanced nanoparticle-based antibacterial delivery for endodontic disinfection: A systematic review and meta-analysis
Nanoparticle-based disinfectants offer a practical advantage in situations where conventional irrigants fall short, particularly in deep dentinal areas and mature biofilms. By improving bacterial elimination and enhancing penetration into complex canal anatomy, these systems may help reduce persistent infection and support more predictable endodontic outcomes. Their favourable biocompatibility also suggests potential as complementary agents within current clinical protocols.
Authors
- Maurya Manjunath (ORCID: https://orcid.org/0000-0001-9563-9269)
- Shashit Shetty Bavabeedu (ORCID: https://orcid.org/0000-0003-4687-8620)
- Ravinder S Saini
- Javier Flores-Fraile (ORCID: https://orcid.org/0000-0002-7739-7179)
- Artak Heboyan
- Seerat Kaura
- Kanwalpreet Kaur
- Mario Alberto Alarcón-Sánchez
Institutions
- Rutgers, The State University of New Jersey (US)
- JSS Academy of Higher Education and Research (IN)
- Universidad de Salamanca (ES)
- Universidad de Guadalajara (MX)
- Rama Dental College Hospital & Research Centre (IN)
- JSS Dental College and Hospital (IN)
- King Khalid University (SA)
- Saveetha University (IN)
Publication Details
- Journal
- Journal of Dentistry
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1016/j.jdent.2026.106347
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00