Assessment of microorganism detection in ThinPrep Papanicolaou tests utilizing the Hologic Genius Digital Diagnostics System

Very high sensitivity was observed for TPPTs across 3 of 4 common microorganisms on the HGDDS, although sensitivity was relatively lower for detecting HSV. Understanding morphologic patterns of various microorganisms in detection misses by the HGDDS may help guide the implementation of AI-assisted cervical cancer screening systems.

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Publication Details

Journal
American Journal of Clinical Pathology
Published
2025-10-23
DOI
https://doi.org/10.1093/ajcp/aqaf126
Primary Topic
AI in cancer detection
Type
article
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article

Assessment of microorganism detection in ThinPrep Papanicolaou tests utilizing the Hologic Genius Digital Diagnostics System

Jonee Matsko, Amy Colaizzi, Yuhong Ye, Chengquan Zhao et al.
American Journal of Clinical Pathology
AI in cancer detection
article

Assessment of microorganism detection in ThinPrep Papanicolaou tests utilizing the Hologic Genius Digital Diagnostics System

Jonee Matsko, Amy Colaizzi, Yuhong Ye, Chengquan Zhao, Liron Pantanowitz, Ali Seemaab
article en

Abstract

Very high sensitivity was observed for TPPTs across 3 of 4 common microorganisms on the HGDDS, although sensitivity was relatively lower for detecting HSV. Understanding morphologic patterns of various microorganisms in detection misses by the HGDDS may help guide the implementation of AI-assisted cervical cancer screening systems.

American Journal of Clinical PathologyVol. 164(6)
Fujian Medical University (CN), University of Pittsburgh (US), Computational Diagnostics (United States) (US), First Affiliated Hospital of Fujian Medical University (CN), University of Pittsburgh Medical Center (US)
Gender equality
Openalex Percentile: Top 17%
AI in cancer detection
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Assessment of microorganism detection in ThinPrep Papanicolaou tests utilizing the Hologic Genius Digital Diagnostics System — Jonee Matsko, Amy Colaizzi, et al. · American Journal of Clinical Pathology (2025) | TGRS Research Map | TGRS