Longitudinal functional connectivity changes across the clinical spectrum of <i>C9orf72</i> hexanucleotide repeat expansion carriers

Though gray matter declines were undetectable over a span of several years, functional connectivity networks changed dynamically in C9orf72+.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_105253
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Longitudinal functional connectivity changes across the clinical spectrum of C9orf72 hexanucleotide repeat expansion carriers

Suvi Häkkinen, Chiadi U. Onyike, Liwen Zhang, Taru Flagan et al.
Alzheimer s & Dementia
Amyotrophic Lateral Sclerosis Research
article

Longitudinal functional connectivity changes across the clinical spectrum of C9orf72 hexanucleotide repeat expansion carriers

Suvi Häkkinen, Chiadi U. Onyike, Liwen Zhang, Taru Flagan, Rosen Hj, Maria Luisa Gorno Tempini, Dana Leichter, Brad F Boeve, Julio C. Rojas, Youjin Jung, Maria Luisa Mandelli, Adam L. Boxer, Leah K. Forsberg, Eliana Marisa Ramos, ARTFL/LEEFTDS/ALLFTD Consortia, Bruce L. Miller, Kejal Kantarci, William W. Seeley, Jennifer S. Yokoyama, Hilary W. Heuer, Suzee E. Lee
article en

Abstract

Though gray matter declines were undetectable over a span of several years, functional connectivity networks changed dynamically in C9orf72+.

Alzheimer s & DementiaVol. 21(S2)
Johns Hopkins University (US), University of California, Los Angeles (US), University of California, San Francisco (US), Shanghai Jiao Tong University (CN), Johns Hopkins Medicine (US), Ruijin Hospital (CN), University Memory and Aging Center (US), Mayo Clinic in Arizona (US)
Openalex Percentile: Top 29%
Amyotrophic Lateral Sclerosis Research
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Longitudinal functional connectivity changes across the clinical spectrum of <i>C9orf72</i> hexanucleotide repeat expansion carriers — Suvi Häkkinen, Chiadi U. Onyike, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS