Impact of mitral valve intervention and frailty on outcomes of severe mitral regurgitation due to severe mitral annular calcification

Patients with severe MR due to MAC were frail with multiple comorbidities and often managed conservatively. Frailty is associated with all-cause mortality, and MV intervention improves survival regardless of frailty status.

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Publication Details

Journal
Progress in Cardiovascular Diseases
Published
2026-01-01
DOI
https://doi.org/10.1016/j.pcad.2026.01.001
Citations
1
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
30.07
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article

Impact of mitral valve intervention and frailty on outcomes of severe mitral regurgitation due to severe mitral annular calcification

B Xu, Mohammad Al Zein, Yuichiro Okushi, R. H. Grimm et al.
1 citations
Progress in Cardiovascular Diseases
Cardiac Valve Diseases and Treatments
30.07
article

Impact of mitral valve intervention and frailty on outcomes of severe mitral regurgitation due to severe mitral annular calcification

B Xu, Mohammad Al Zein, Yuichiro Okushi, R. H. Grimm, Brian P. Griffin, Shinya Unai, Gösta B. Pettersson, A. Marc Gillinov, Per Wierup
article en
1 citations

Abstract

Patients with severe MR due to MAC were frail with multiple comorbidities and often managed conservatively. Frailty is associated with all-cause mortality, and MV intervention improves survival regardless of frailty status.

Progress in Cardiovascular Diseases
Cleveland Clinic (US)
Good health and well-being
Openalex Percentile: Top 2%
Cardiac Valve Diseases and Treatments
30.07
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