CRISPR/CAS9-based gene editing in cancer therapy: A systematic review and meta-analysis on current status and future directions
From the findings of this work, it can be concluded that CRISPR/Cas9 is a promising tool, but there are several limitations including off target effects, delivery systems and ethical issues that need to be solved in order to improve the clinical significance.
Authors
- Shafee Ur Rehman (ORCID: https://orcid.org/0000-0001-5238-5211)
- Ghulam Abbas (ORCID: https://orcid.org/0009-0008-1173-791X)
Institutions
- Ala-Too International University (KG)
- Mass General Brigham (US)
Publication Details
- Journal
- Medicine
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1097/md.0000000000047114
- Citations
- 1
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 22.24