Psychometric Evaluation of Skin Pain and Sleep Disturbance Numeric Rating Scales in Moderate-to-Severe Atopic Dermatitis
The AD SP-NRS and SD-NRS are reliable, valid, and responsive measures for assessing moderate-to-severe AD in adults and adolescents in clinical trials. The meaningful change thresholds identified in this study can be used in future clinical trials to interpret treatment effects.
Authors
- Kimberly M. Deininger (ORCID: https://orcid.org/0000-0003-2729-7097)
- Angela Rylands (ORCID: https://orcid.org/0000-0002-7790-4724)
- Shanshan Qin (ORCID: https://orcid.org/0000-0002-8574-5508)
- Lauren Nelson
- LORI MCLEOD
- Andrew Blauvelt
- Joshua Porter
- Alexis Sohn
Institutions
- Amgen (United States) (US)
- Kyowa Kirin International (United Kingdom) (GB)
- Maryland Department of Natural Resources (US)
- RTI Health Solutions (US)
Publication Details
- Journal
- Dermatology and Therapy
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1007/s13555-025-01634-5
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amgen