Systematic review of Alzheimer's Disease (AD) biomarker studies in those with intellectual and developmental disability (I/DD): Evidence gap mapping

The lack of data from representative samples of individuals with I/DD limits the generalizability of current study outcomes. Future studies should include a broader range of I/DD presentations. In addition to non-DS I/DD presentations, sex differences and novel biomarkers such as beta synuclein and VAMP-2 are promising future directions.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_106296
Primary Topic
Down syndrome and intellectual disability research
Type
article
Field-Weighted Citation Impact
0.00
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article

Systematic review of Alzheimer's Disease (AD) biomarker studies in those with intellectual and developmental disability (I/DD): Evidence gap mapping

Ney Alliey‐Rodriguez, Lubnaa Abdullah, Gladys Elena Maestre, Emma Elizondo et al.
Alzheimer s & Dementia
Down syndrome and intellectual disability research
article

Systematic review of Alzheimer's Disease (AD) biomarker studies in those with intellectual and developmental disability (I/DD): Evidence gap mapping

Ney Alliey‐Rodriguez, Lubnaa Abdullah, Gladys Elena Maestre, Emma Elizondo, Ney Alexander Alliey, James Hall
article en

Abstract

The lack of data from representative samples of individuals with I/DD limits the generalizability of current study outcomes. Future studies should include a broader range of I/DD presentations. In addition to non-DS I/DD presentations, sex differences and novel biomarkers such as beta synuclein and VAMP-2 are promising future directions.

Alzheimer s & DementiaVol. 21(S2)
University of North Texas (US), University of North Texas Health Science Center (US), The University of Texas Rio Grande Valley (US)
Quality Education
Openalex Percentile: Top 24%
Down syndrome and intellectual disability research
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