Levels of and changes in psychosis symptoms and clinical insight: Exploring the impact of differential antipsychotic mechanisms

Symptom reduction is associated with improved insight, with early changes in positive symptoms exerting the fastest effect. Despite symptom improvement, aripiprazole PDA treatment was linked to less insight gain than DA treatment. These preliminary findings warrant further study.

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Publication Details

Journal
Psychiatry Research
Published
2026-01-09
DOI
https://doi.org/10.1016/j.psychres.2026.116948
Citations
1
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
33.12
Controls
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article

Levels of and changes in psychosis symptoms and clinical insight: Exploring the impact of differential antipsychotic mechanisms

Rune A. Kroken, Lena Antonsen Stabell, Kenneth Hugdahl, Eirik Kjelby et al.
1 citations
Psychiatry Research
Schizophrenia research and treatment
33.12
article

Levels of and changes in psychosis symptoms and clinical insight: Exploring the impact of differential antipsychotic mechanisms

Rune A. Kroken, Lena Antonsen Stabell, Kenneth Hugdahl, Eirik Kjelby, Erik Johnsen, Else-Marie Løberg, Inge Joa, Rolf Gjestad, Solveig Klæbo Reitan, Maria Rettenbacker
article en
1 citations

Abstract

Symptom reduction is associated with improved insight, with early changes in positive symptoms exerting the fastest effect. Despite symptom improvement, aripiprazole PDA treatment was linked to less insight gain than DA treatment. These preliminary findings warrant further study.

Psychiatry ResearchVol. 358
Innsbruck Medical University (AT), Stavanger University Hospital (NO), Haukeland University Hospital (NO), St Olav's University Hospital (NO), University of Bergen (NO)
Good health and well-being
Openalex Percentile: Top 2%
Schizophrenia research and treatment
33.12
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Levels of and changes in psychosis symptoms and clinical insight: Exploring the impact of differential antipsychotic mechanisms — Rune A. Kroken, Lena Antonsen Stabell, et al. · Psychiatry Research (2026) | TGRS Research Map | TGRS