Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease
GFAP concentrations are higher in the cerebral phenotype and increase over time in young children. These data can be used to formulate biomarker qualification and context-of-use in AxD.
Authors
- Joshua Joung (ORCID: https://orcid.org/0009-0000-4151-4655)
- Walter G. Faig
- Asako Takanohashi (ORCID: https://orcid.org/0000-0003-3292-1595)
- Kaley Arnold
- Amy T Waldman
- Amy Pizzino
- Geraldine W. Liu
- Sarah Woidill
- Sona Narula
Institutions
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1002/acn3.70305
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Pennsylvania
- Ionis Pharmaceuticals
- National Institutes of Health
- Perelman School of Medicine, University of Pennsylvania