Topically administered macrocyclic lactone products, including eprinomectin, demonstrate comparable neurological safety in cats based on pharmacovigilance data

These findings supported the conclusion that ML-containing products (including eprinomectin-containing products) and emodepside are comparable in the frequencies and types of neurological AEs associated with feline topical parasiticide products described as substrates for P-glycoprotein transporters.

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Publication Details

Journal
Journal of the American Veterinary Medical Association
Published
2026-01-09
DOI
https://doi.org/10.2460/javma.25.10.0669
Primary Topic
Helminth infection and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Topically administered macrocyclic lactone products, including eprinomectin, demonstrate comparable neurological safety in cats based on pharmacovigilance data

Timothy S. Frana, Mark J. Novotny, Timothy G. Geary, Marcelo Silva
Journal of the American Veterinary Medical Association
Helminth infection and control
article

Topically administered macrocyclic lactone products, including eprinomectin, demonstrate comparable neurological safety in cats based on pharmacovigilance data

Timothy S. Frana, Mark J. Novotny, Timothy G. Geary, Marcelo Silva
article en

Abstract

These findings supported the conclusion that ML-containing products (including eprinomectin-containing products) and emodepside are comparable in the frequencies and types of neurological AEs associated with feline topical parasiticide products described as substrates for P-glycoprotein transporters.

Journal of the American Veterinary Medical Association
Université Sainte-Anne (CA), Queen's University Belfast (GB), Boehringer Ingelheim (Germany) (DE), Boehringer Ingelheim (United States) (US), McGill University (CA)
Openalex Percentile: Top 92%
Helminth infection and control
DOISourceOpenAlex
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Topically administered macrocyclic lactone products, including eprinomectin, demonstrate comparable neurological safety in cats based on pharmacovigilance data — Timothy S. Frana, Mark J. Novotny, et al. · Journal of the American Veterinary Medical Association (2026) | TGRS Research Map | TGRS