Clinical management of bilateral functional adrenal adenomas

Adrenocortical tumors are uncommon in the pediatric population. We report a case of a pediatric patient with Beckwith Wiedemann Syndrome (BWS) who was found to have bilateral functional adrenal adenomas: one mineralocorticoid-secreting and one androgen-secreting. The patient ultimately underwent staged surgical resection of both masses, resulting in marked reduction in hormone levels. This case highlights the pathophysiology of adrenal adenomas, association between BWS and adrenal masses, and treatment challenges of bilateral adrenal masses.

Authors

Institutions

Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-12-23
DOI
https://doi.org/10.1093/jscr/rjaf1051
Primary Topic
Genetic Syndromes and Imprinting
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Clinical management of bilateral functional adrenal adenomas

William Middlesworth, Brooks Melnyk, Caitlin J Cain-Trivette, Jee-Young Nina Ham et al.
Journal of Surgical Case Reports
Genetic Syndromes and Imprinting
article

Clinical management of bilateral functional adrenal adenomas

William Middlesworth, Brooks Melnyk, Caitlin J Cain-Trivette, Jee-Young Nina Ham, Claire Gerall
article en

Abstract

Adrenocortical tumors are uncommon in the pediatric population. We report a case of a pediatric patient with Beckwith Wiedemann Syndrome (BWS) who was found to have bilateral functional adrenal adenomas: one mineralocorticoid-secreting and one androgen-secreting. The patient ultimately underwent staged surgical resection of both masses, resulting in marked reduction in hormone levels. This case highlights the pathophysiology of adrenal adenomas, association between BWS and adrenal masses, and treatment challenges of bilateral adrenal masses.

Journal of Surgical Case ReportsVol. 2026(1)
Morgan Stanley Children's Hospital (US)
Good health and well-being
Openalex Percentile: Top 23%
Genetic Syndromes and Imprinting
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.